Population
22 individuals from three families in which cases of poliomyelitis had recently occurred.
Design
Cohort
Follow-up
3 weeks
Authors
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Antibodies may limit subclinical poliomyelitis in older contacts; leaves open causal role and prospective validation before guiding immunity strategies.
The presence of serum antibodies appears effective in limiting subclinical infection with poliomyelitis virus among familial contacts.
Brown et al. (1951) studied this question.
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