December 20, 2004Diabetic Medicine
NT‐proBNP in normoalbuminuric patients with Type 2 diabetes mellitus
Population
90 subjects: 60 Type 2 diabetic patients without albuminuria and 30 age- and sex-matched normal controls…
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
May indicate LV remodeling in hypertensive T2D without albuminuria; hypothesis-generating and requires validation before clinical adoption.
Structured PICO
P
Population
90 subjects: 60 Type 2 diabetic patients without albuminuria (30 normotensive, 30 hypertensive) and 30 age- and sex-matched normal controls. Exclusion criteria: cardiac symptoms and ejection fraction < 55%.
O
Outcome
NT-proBNP levels and their relation to hypertension and diastolic function assessed by echocardiographysurrogate
NT-proBNP is significantly increased in hypertensive, normoalbuminuric patients with Type 2 diabetes, related to left ventricular hypertrophy and increased left atrial and ventricular diameters rather than diastolic dysfunction.
Cite This Study
Andersen et al. (2004) studied this question.