Why the study?
Is a protocol for ambulatory investigation safe and effective for predicted low-risk patients with possible pulmonary embolism?
Is a protocol for ambulatory investigation safe and effective for predicted low-risk patients with possible pulmonary embolism?
A protocol for ambulatory investigation of low-risk patients with possible PE appears feasible and safe, though larger prospective studies are needed.
Answers are grounded in this paper and cite their sources.
Supports ambulatory PE protocols in low-risk patients; leaves open broader adoption without randomized confirmation.
BACKGROUND: Patients with possible pulmonary embolism (PE) commonly present to acute medical services. Research has led to the identification of low-risk patients suitable for ambulatory management. We report on a protocol designed to select low-risk patients for ambulatory investigation if confirmatory imaging is not available that day. METHODS: The protocol was piloted in the Emergency Department and Medical Assessment Area at the Royal Infirmary of Edinburgh. We retrospectively analysed electronic patient records in an open observational audit of all patients managed in the ambulatory arm over five months of use. RESULTS: We analysed 45 patients' records. Of these, 91.1% required imaging to confirm or refute PE, 62.2% received a computed tomography pulmonary angiogram (CTPA). In 25% of patients, PE was confirmed with musculoskeletal pain (22.7%), and respiratory tract infection (15.9%) the next most prevalent diagnoses. Alternative diagnoses was provided by CTPA in 32% of cases. We identified no adverse events or readmissions but individualised follow-up was not attempted. CONCLUSIONS: The data from this audit suggests this protocol can be applied to select and manage low-risk patients suitable for ambulatory investigation of possible PE. A larger prospective comparative study would be required to accurately define the safety and effectiveness of this protocol.
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McDonald et al. (2011) studied this question.
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