Why the study?
Iatrogenic metastases from tumor implantation due to surgical cross-contamination are an unfortunate complication requiring preventive techniques and oncologic surgical principles to reduce their likelihood.
Highlights the risk of iatrogenic metastasis at donor flap sites during sarcoma resection and emphasizes the need for strict oncologic surgical techniques to prevent cross-contamination.
Potential donor-site seeding risk warrants surgical vigilance in sarcoma cases; single case report leaves open need for systematic prevention data.
An 81-year-old woman with multiply recurrent undifferentiated pleomorphic sarcoma of the foot underwent wide excision and reconstruction with an anterolateral thigh free flap. Six years postoperatively, she developed biopsy-proven recurrence within the harvest site. No other sites of disease were detected on staging workup. The flap site recurrence was attributed to iatrogenic implantation at the time of harvesting. Iatrogenic metastases are thought to be caused by tumor implantation, which may be attributable to cross-contamination from instrumentation and surgical techniques. In the present article, we highlight preventive techniques and oncologic surgical principles intended to reduce the likelihood of iatrogenic metastasis. Increased awareness by all members of the surgical team may prevent this unfortunate complication.
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LiBrizzi et al. (2021) studied this question.
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