Key result
Isolated minor non-specific ST-segment and T-wave abnormalities were significantly associated with the extent of common carotid intima-media thickness (OR 1.25; 95% CI 1.06-1.48; p<0.01).
Why the study?
Do isolated minor non-specific ST-segment and T-wave abnormalities associate with subclinical atherosclerosis in a middle-aged biracial population?
Cross-Sectional (n=2,175)
Do isolated minor non-specific ST-segment and T-wave abnormalities associate with subclinical atherosclerosis in a middle-aged biracial population?
Odds Ratio: 1.25 (95% CI 1.06–1.48)
p-value: p=< 0.01
Isolated minor non-specific ST-segment and T-wave abnormalities are associated with increased common carotid intima-media thickness, but not coronary artery calcium, suggesting a potential link to specific types of subclinical atherosclerosis.
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Minor ECG changes should not alter risk assessment; extends cross-sectional links to carotid IMT but leaves causal and prognostic value open.
Walsh et al. (2012) conducted a cross-sectional in Subclinical atherosclerosis (n=2,175). Isolated minor non-specific ST-segment and T-wave abnormalities (NSSTTAs) vs. Absence of NSSTTAs was evaluated on Extent of common carotid intima-media thickness (CC-IMT) (OR 1.25, 95% CI 1.06-1.48, p=< 0.01). Isolated minor non-specific ST-segment and T-wave abnormalities were significantly associated with the extent of common carotid intima-media thickness (OR 1.25; 95% CI 1.06-1.48; p<0.01).
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