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Synthesize current neuroanatomical and neurophysiological evidence regarding the generation and modulation of respiratory rhythm across the lower brainstem and spinal cord.

August 17, 2016The Journal of Physiological SciencesOpen Access

The respiratory control mechanisms in the brainstem and spinal cord: integrative views of the neuroanatomy and neurophysiology

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Synthesize current neuroanatomical and neurophysiological evidence regarding the generation and modulation of respiratory rhythm across the lower brainstem and spinal cord.
Narrative review evaluating accumulated literature on medullary respiratory rhythm generators and descending efferent circuits.
Respiratory rhythm generation is driven by specialized medullary networks that undergo continuous modulation from diverse nuclei across the lower brainstem.
Premotor efferent circuits transmit patterned rhythmogenic signals from the brainstem to spinal cord motor pools to coordinate mechanical breathing movements.

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Implication

Narrative review reveals integrative neural circuits governing respiratory rhythm in the central nervous system, highlighting coordinated brainstem and spinal networks in breathing regulation.

Cite This Study

Ikeda et al. (2016) studied this question.

synapsesocial.com/papers/6a8c1ff7f71b672e3df4b79d https://doi.org/10.1007/s12576-016-0475-y

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Implication

Narrative review reveals integrative neural circuits governing respiratory rhythm in the central nervous system, highlighting coordinated brainstem and spinal networks in breathing regulation.

The respiratory control mechanisms in the brainstem and spinal cord: integrative views of the neuroanatomy and neurophysiology

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Discussion

Implication

Cite This Study

The respiratory control mechanisms in the brainstem and spinal cord: integrative views of the neuroanatomy and neurophysiology

Key Points

Discussion

Implication

Cite This Study

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