Key result
Young Taiwanese-Chinese women with PCOS did not have greater carotid intima-media thickness than controls, and androstenedione was inversely associated with CIMT.
Why the study?
Does polycystic ovary syndrome or endogenous androgen levels affect carotid intima-media thickness in young women?
Case-Control (n=85)
Does polycystic ovary syndrome or endogenous androgen levels affect carotid intima-media thickness in young women?
Young women with PCOS do not exhibit increased carotid intima-media thickness compared to controls, despite having more atherosclerosis risk factors, and androstenedione is inversely associated with CIMT.
Polycystic ovary syndrome (PCOS) is a common and complex female endocrinopathy that is associated with multiple vascular risk factors. Our objective was to investigate the relationship between carotid intima-media thickness (CIMT) and endogenous androgens in young Taiwanese-Chinese women with PCOS. We measured CIMT with B-mode ultrasound in 42 young PCOS patients and 43 controls. Atherosclerosis-associated profiles and endocrinological parameters were also measured. The results showed that although Taiwanese-Chinese PCOS patients tend to possess more risk factors for atherosclerosis than controls, there was no evidence to support that they have a greater CIMT at this age. Furthermore, androstenedione appears to be inversely associated with CIMT.
No takes yet. Share an insight, caveat, or question.
Teng et al. (2012) conducted a case-control in Polycystic ovary syndrome (PCOS) (n=85). Polycystic ovary syndrome (PCOS) vs. Controls was evaluated on Carotid intima-media thickness (CIMT). Young Taiwanese-Chinese women with PCOS did not have greater carotid intima-media thickness than controls, and androstenedione was inversely associated with CIMT.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: