What does this research mean for the field?

Asthma destabilization in children during armed conflicts is a multifactorial process driven by the synergistic interaction of chronic psychological stress, environmental hazards, and healthcare disruption. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Synthesize evidence on the psychoneuroimmunological, environmental, and behavioral mechanisms driving loss of asthma control in children during armed conflict and outline clinical management strategies.

August 24, 2026Allergy Asthma and Clinical ImmunologyOpen Access

Synergism of triggers for loss of asthma control in children during wartime

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Authors

OBOksana Boyarchuk ICIryna Chornomydz VUVira Uska

Discussion

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Overview

Narrative review reveals synergistic psychological, environmental, and healthcare disruptions driving asthma exacerbations in children during wartime, highlighting the need for multifaceted care.

Key Points

Synthesize evidence on the psychoneuroimmunological, environmental, and behavioral mechanisms driving loss of asthma control in children during armed conflict and outline clinical management strategies.
Conducted a targeted narrative review searching PubMed/MEDLINE, Scopus, Web of Science, Google Scholar, and the Vernadsky National Library of Ukraine.
Integrated conflict-related pediatric asthma studies with mechanistic research in psychoneuroimmunology and environmental health alongside international clinical guidelines.
Chronic psychological stress alters brain-lung axis signaling, promoting neuroimmune dysregulation and diminishing glucocorticoid responsiveness.
Environmental exposures, including particulate matter, combustion byproducts, damp shelter conditions, and localized allergens, directly amplify airway inflammation.
Disrupted healthcare access, forced displacement, and social instability compound physiological triggers by reducing medication adherence and care continuity.

Cite This Study

Boyarchuk et al. (2026) studied this question.

synapsesocial.com/papers/6a8c23d1bca056c88e6dfe5b https://doi.org/10.1186/s13223-026-01060-y

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August 24, 2026Allergy Asthma and Clinical ImmunologyOpen Access

Synergism of triggers for loss of asthma control in children during wartime

View Full Paper

Ask AI

Bookmark

Authors

OBOksana Boyarchuk ICIryna Chornomydz VUVira Uska

Discussion

Member takes

Overview

Narrative review reveals synergistic psychological, environmental, and healthcare disruptions driving asthma exacerbations in children during wartime, highlighting the need for multifaceted care.

Key Points

Synthesize evidence on the psychoneuroimmunological, environmental, and behavioral mechanisms driving loss of asthma control in children during armed conflict and outline clinical management strategies.
Conducted a targeted narrative review searching PubMed/MEDLINE, Scopus, Web of Science, Google Scholar, and the Vernadsky National Library of Ukraine.
Integrated conflict-related pediatric asthma studies with mechanistic research in psychoneuroimmunology and environmental health alongside international clinical guidelines.
Chronic psychological stress alters brain-lung axis signaling, promoting neuroimmune dysregulation and diminishing glucocorticoid responsiveness.
Environmental exposures, including particulate matter, combustion byproducts, damp shelter conditions, and localized allergens, directly amplify airway inflammation.
Disrupted healthcare access, forced displacement, and social instability compound physiological triggers by reducing medication adherence and care continuity.

Cite This Study

Boyarchuk et al. (2026) studied this question.

synapsesocial.com/papers/6a8c23d1bca056c88e6dfe5b https://doi.org/10.1186/s13223-026-01060-y

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