Answers are grounded in this paper and cite their sources.
Synthesis of telechelic polymer of β-CD-poly(ethylene glycol) using poly(ethylene glycol) and mono-6- O -tosyl-β-CD is described. Three β-lactam antibiotics: ampicillin (Amp), amoxicillin (Amo), and cephalexin (Ceph) were attached to β-CD-poly(ethylene glycol) and to unmodified β-CD as the carrier agents. Structures of these prodrugs were confirmed using spectroscopic methods. The profiles of drug’s release indicated that the isolated pro-drugs could have potential applications for controlled drug release as oral drug delivery systems.
No takes yet. Share an insight, caveat, or question.
Namazi et al. (2006) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: