Key result
Acute type A dissection surgery yields ~75% NYHA class I living at home at 1 year.
Why the study?
What are the 1-year functional outcomes and mortality rates in patients after surgery for acute Stanford type A aortic dissection?
Observational (n=642)
What are the 1-year functional outcomes and mortality rates in patients after surgery for acute Stanford type A aortic dissection?
Surgery for acute Stanford type A aortic dissection is associated with favorable 1-year functional outcomes, with the majority of patients living unassisted at home and stroke survivors showing good neurological recovery.
Background Our aim was to report the functional outcome of Stanford type A aortic dissection (TAAD) after 1 year as well as morbidity and mortality. Methods and Results This is a retrospective analysis including 642 patients with TAAD from January 2005 to December 2021. Mean age at TAAD was 62 years (95% CI, 61–63), and 30% of the population were women. One year after surgery for TAAD, 75% of patients were living at home with New York Heart Association functional class I. No patients were observed with New York Heart Association functional class IV. Less than 2% resided in an assisted‐living facility. Eighty‐five percent of nonretired patients had returned to work. Two hundred twelve (33%) patients were retired after 1 year at a mean age of 73 years (95% CI, 72–74). Stroke (defined as any kind of neurological symptoms) occurred in 148 (23%) patients and was the cause of death in 33 patients. Of the remaining patients with stroke, 115 (30%) had no residual limitations 1 year after TAAD. The cross‐clamp time was significantly higher in patients with stroke (98 minutes [95% CI, 94.0–101.1] in patients without stroke versus 106 minutes [95% CI, 98.5–114.1] in patients with stroke; P =0.026). Sixty‐nine percent of patients with stroke lived at home, 28% lived at home with support, and 3% lived in an assisted‐living facility. One year after stroke, 77% of the patients achieved a modified Rankin Scale score ≤2, whereas no patient had a modified Rankin Scale score of 5. There was no significant correlation between sex and recovery rate ( P =0.48). However, experiencing a stroke significantly increased the likelihood of residing in an assisted‐living facility or receiving support at home 1 year after TAAD (odds ratio, 9.46 [95% CI, 5.06–17.70]; P <0.001). Thirty‐day mortality was 11.8%, and 92 patients (14%) died within the first year after TAAD. There was no significant sex difference in mortality ( P =0.101). Conclusions One year after surgery for Stanford acute type A aortic dissection, almost 3 out of 4 patients lived unassisted at home. Stroke survivors have a favorable outcome, with the majority having mild or no residual neurological deficits at 1 year.
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Yıldız et al. (2025) conducted an observational in Acute Stanford type A aortic dissection (n=642). Surgery for acute Stanford type A aortic dissection was evaluated on Living at home with New York Heart Association functional class I at 1 year. Surgery for acute Stanford type A aortic dissection resulted in 75% of patients living at home with NYHA class I at 1 year; stroke increased the need for assistance (OR 9.46; 95% CI 5.06-17.70).
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