Key result
Enhanced Recovery Programs applied to laparoscopic surgery attenuate the inflammatory surgical stress response, as evidenced by reduced Interleukin-6 and C-Reactive Protein levels compared to standard care.
Why the study?
Does an Enhanced Recovery Program reduce the surgical stress response in patients undergoing laparoscopic surgery?
Systematic Review (n=632)
Does an Enhanced Recovery Program reduce the surgical stress response in patients undergoing laparoscopic surgery?
Enhanced Recovery Programs applied to laparoscopic surgery attenuate the surgical stress response, evidenced by lower inflammatory markers and better preserved nutritional status.
Answers are grounded in this paper and cite their sources.
Supports integrating enhanced recovery protocols to minimize physiologic surgical trauma; extends the known clinical benefits of.
Contextul: Programul mbuntit de recuperare (Enhanced Recovery Program ERP) este un protocol multimodal perioperator. Fezabilitatea i beneficiile rezultatelor sale pe termen scurt au fost raportate la scar larg. mbuntirile descrise, ca de exemplu durat mai mic a spitalizrii i reluarea timpurie a funciilor corpului, reprezint consecina unui rspuns atenuat la stresul chirurgical. Atunci cnd rspunsul este necontrolat, acesta poate duce la complicaii postoperatorii i la rezultate slabe pe termen lung. Rspunsul la stresul chirurgical poate fi monitorizat cu uurin prin analiza mediatorilor din fluxul sanguin. Dovezile actuale nu au relevat pn acum dac programul de recuperare permite msurarea reducerii stresului chirurgical. n cadrul acestui studiu, am cutat articole tiinifice care s investigheze rspunsul la stresul chirurgical i programul de recuperare aplicat n urma procedurilor minim-invazive de elecie, pentru a nelege mai bine nivelul evidenei privind eficiena programului de recuperare. Material i metod: O analiz sistematic a literaturii a fost efectuat folosind baze de date PubMed, Cochrane, EMBASE i Google Scholar, urmnd liniile directoare PRISMA (Preferred Reporting Items for Systematic Review and Meta-analysis). Studiile includ analiza rspunsului la stresul chirurgical i programul de recuperare aplicat pacienilor care au suferit intervenii chirurgicale laparoscopice n diferite specialiti. Au fost incluse opt studii, cu un total de 632 de pacieni.
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Crippa et al. (2018) conducted a systematic review in Elective laparoscopic surgery (n=632). Enhanced Recovery Program (ERP) vs. Standard perioperative care was evaluated on Surgical stress response (inflammatory, endocrine, and nutritional markers). Enhanced Recovery Programs applied to laparoscopic surgery attenuate the inflammatory surgical stress response, as evidenced by reduced Interleukin-6 and C-Reactive Protein levels compared to standard care.
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