Why the study?
Does the intraoperative period alter critical oxygen delivery and oxygen extraction ratio compared to the preoperative period in high-risk surgical patients?
Population
20 high-risk surgical patients undergoing major noncardiac surgery
Comparison
Intraoperative period (anesthesia) vs Preoperative period
Design
Cohort
Follow-up
perioperative period
Authors
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May increase tissue hypoxia risk intraoperatively; leaves open whether DO2 optimization alters outcomes in high-risk surgery.
Does the intraoperative period alter critical oxygen delivery and oxygen extraction ratio compared to the preoperative period in high-risk surgical patients?
The intraoperative period in high-risk surgical patients is associated with a significant reduction in tissue oxygen extraction ability, potentially increasing the risk of tissue oxygenation debt.
Lugo et al. (1993) studied this question.
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