Key result
Preoperative frailty or prefrailty was significantly associated with cognitive decline at 12 months following total hip joint replacement (OR 2.00; 95% CI 1.26-3.17).
Why the study?
Preoperative frailty is known to associate with poor postoperative outcomes, but whether this includes cognitive decline after anesthesia and surgery was unclear.
Does preoperative frailty predict postoperative neurocognitive disorders in older adults undergoing elective total hip joint replacement?
Population
300 participants aged ≥60 scheduled for elective total hip joint replacement
Comparison
Preoperative frailty or prefrailty vs non-frailty
Design
Retrospective observational study (secondary analysis)
Follow-up
12 months
Authors
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May support frailty screening before hip replacement; leaves open whether interventions modify cognitive risk.
Observational (n=300)
Does preoperative frailty predict postoperative neurocognitive disorders in older adults undergoing elective total hip joint replacement?
Odds Ratio: 2 (95% CI 1.26–3.17)
Preoperative frailty is associated with long-term postoperative cognitive decline in older adults undergoing total hip replacement, highlighting the importance of preoperative frailty screening.
Evered et al. (2020) conducted an observational in Elective total hip joint replacement (n=300). Preoperative frailty or prefrailty vs. No frailty was evaluated on Cognitive decline at 12 months (OR 2.00, 95% CI 1.26-3.17). Preoperative frailty or prefrailty was significantly associated with cognitive decline at 12 months following total hip joint replacement (OR 2.00; 95% CI 1.26-3.17).
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