Intravenous tirofiban successfully dissolved a massive intracoronary thrombus in a patient with angiographically normal coronary arteries.
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May support tirofiban in refractory thrombus; hypothesis-generating and should not change practice.
We report a 64-year-old Turkish man who presented with unstable angina pectoris. Coronary angiography revealed massive intracoronary thrombus, which completely occluded the distal part of the left circumflex coronary artery. The thrombotic segment and the rest of the coronary tree were free of atherosclerosis. The patient was treated with intravenous tirofiban, a glycoprotein IIb/IIIa inhibitor. A control angiography was performed one week later and showed total dissolution of the thrombus with tirofiban therapy.
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Özeren et al. (2004) studied this question.
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