Key result
Enhanced recovery after surgery (ERAS) protocols significantly reduced 30-day morbidity and mortality compared to conventional care in patients undergoing liver surgeries.
Why the study?
Enhanced recovery after surgery programs aim to improve postoperative outcomes, but their impact following liver surgeries needed evaluation.
Do Enhanced recovery after surgery (ERAS) protocols reduce 30-day morbidity and mortality in patients undergoing liver surgery compared to conventional care?
Meta-Analysis (n=1,289)
Do Enhanced recovery after surgery (ERAS) protocols reduce 30-day morbidity and mortality in patients undergoing liver surgery compared to conventional care?
Absolute Event Rate: 19.2% vs 25.4%
p-value: p=<0.001
The adoption of ERAS protocols in liver surgeries significantly reduces 30-day morbidity, hospital stay, recovery time, and hospital costs compared to conventional care.
Supports ERAS adoption as standard in liver surgery; extends Level 1 evidence from other fields.
BACKGROUND Enhanced recovery after surgery (ERAS) programs aim to improve postoperative outcomes.. This metaanalysis aims to evaluate the impact of ERAS programmes on outcomes following liver surgeries. METHODS EMBASE, MEDLINE, PubMed and the Cochrane Database were searched for studies comparing outcomes in patients undergoing liver surgery utilizing ERAS principles with those patients receiving conventional care. The primary outcome was occurrence of 30 day morbidity and mortality. Secondary outcomes included length of stay, functional recovery, readmission rates,time to pass flatus,blood loss and hospital costs. RESULTS Ten articles were included in the metaanalysis. 30 days morbidity and mortality was significantly less in ERAS group.Hospital stay, time to pass flatus, time to complete recovery and hospital costs were also significantly reduced due to ERAS protocols. Blood loss and readmission rates were also significantly less in ERAS group. CONCLUSIONS The adoption of ERAS protocols significantly reduced morbidity, mortality hospital stay, readmission rates, time to recovery, hospital costs, time to pass flatus, blood loss and readmission rates.
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Vasavada et al. (2020) conducted a meta-analysis in Liver surgery (n=1,289). Enhanced recovery after surgery (ERAS) protocols vs. Conventional care was evaluated on 30-day morbidity (p=<0.001). Enhanced recovery after surgery (ERAS) protocols significantly reduced 30-day morbidity and mortality compared to conventional care in patients undergoing liver surgeries.
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