Key result
BMI ≥24.0 kg/m2 (OR 1.514; 95% CI 1.057-2.167), single segmentectomy, bilobectomy, and right lung lobe surgery were independent risk factors for postoperative pulmonary complications.
Why the study?
The study investigated perioperative risk factors of postoperative pulmonary complications after minimally invasive anatomic resection for lung cancer.
What are the independent risk factors for postoperative pulmonary complications in lung cancer patients undergoing minimally invasive anatomic lung resection?
Cohort (n=729)
What are the independent risk factors for postoperative pulmonary complications in lung cancer patients undergoing minimally invasive anatomic lung resection?
Odds Ratio: 1.514 (95% CI 1.057–2.167)
p-value: p=0.024
BMI ≥24.0 kg/m2, specific resection types, and right lung lobe surgery are independent risk factors for postoperative pulmonary complications after minimally invasive lung resection.
Identifies higher-risk patients for PPCs after minimally invasive resection; hypothesis-generating and requires prospective validation before guiding practice.
Purpose: This study investigated the perioperative risk factors of postoperative pulmonary complications (PPCs) after minimally invasive anatomic resection for lung cancer. Patients and methods: We retrospectively reviewed the data from medical records of 729 lung cancer patients undergoing minimally invasive anatomic lung resections between January 2017 and December 2017. Univariate and binary logistic regression analyses were performed to select the independent risk factors for PPCs during the patient’s postoperative hospitalization after surgery. Results: The incidence of PPCs was 24.8% (n=181/729). No patient died during the period of hospitalization. Logistic regression analysis revealed that body mass index (BMI) $24.0 kg/m 2 (vs <24.0 kg/m 2 : OR 1.514, 95% CI 1.057–2.167, P =0.024), single segmentectomy (vs single lobectomy: OR 2.115, 95% CI 1.150–3.891, P =0.016), bilobectomy or combined lobectomy and segmentectomy (vs single lobectomy: OR 2.731, 95% CI 1.013–7.361, P =0.047), and right lung lobe surgery (vs left lung lobe surgery: OR 1.519, 95% CI 1.046–2.205, P =0.028) were independent risk factors for PPCs in lung cancer patients who received minimally invasive anatomic lung resections. Conclusion: Individual factors such as BMI ≥24.0 kg/m 2 , single segmentectomy, bilobectomy or combined lobectomy and segmentectomy, and right lung lobe surgery were independent risk factors of PPCs, which should be helpful for risk stratification, patient counseling, and perioperative care for lung cancer patients.
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Yang et al. (2019) conducted a cohort in lung cancer (n=729). BMI ≥24.0 kg/m2 vs. BMI <24.0 kg/m2 was evaluated on postoperative pulmonary complications (PPCs) (OR 1.514, 95% CI 1.057-2.167, p=0.024). BMI ≥24.0 kg/m2 (OR 1.514; 95% CI 1.057-2.167), single segmentectomy, bilobectomy, and right lung lobe surgery were independent risk factors for postoperative pulmonary complications.
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