Key result
Perceived stress was a significant predictor of neutrophil activity at follow-up, with higher stress levels associated with higher neutrophil activity in patients undergoing cardiopulmonary bypass.
Population
82 patients undergoing heart surgery involving cardiopulmonary bypass surgery (CPB)
Design
Cohort
Follow-up
6 weeks after discharge
Authors
Loading...
Hypothesis-generating for stress modulation of perioperative immunity; prospective trials needed before clinical adoption.
Observational (n=82)
Higher levels of perceived stress are significantly associated with increased neutrophil activity in patients undergoing cardiopulmonary bypass surgery.
Ellard et al. (2006) conducted an observational in Heart surgery involving cardiopulmonary bypass surgery (CPB) (n=82). Perceived stress was evaluated on Neutrophil activity quantified using nitro-blue tetrazolium (NBT) and luminol-dependant chemiluminescence. Perceived stress was a significant predictor of neutrophil activity at follow-up, with higher stress levels associated with higher neutrophil activity in patients undergoing cardiopulmonary bypass.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: