Key result
Postoperative atrial fibrillation occurs in 25% to 40% of patients, and available evidence suggests that only beta-blockers can be recommended for its prevention after cardiac surgery.
Why the study?
Do beta-blockers prevent postoperative atrial fibrillation in patients undergoing cardiac surgery?
Do beta-blockers prevent postoperative atrial fibrillation in patients undergoing cardiac surgery?
Beta-blockers are the only broadly recommended therapy for preventing postoperative atrial fibrillation in cardiac surgery patients based on current evidence of safety and efficacy.
Supports beta-blocker prophylaxis for POAF after cardiac surgery; leaves open efficacy of alternatives pending stronger trials.
A number of advances in surgical and anesthetic techniques have reduced the risk for patients undergoing cardiac surgery. However, postoperative atrial fibrillation remains common, with an incidence ranging between 25% and 40%. It is associated with an increased incidence of congestive heart failure, renal insufficiency, and stroke that prolongs hospitalization and increases rates of readmission after discharge. Consequently, there has been great interest in strategies to prevent this arrhythmia. When both safety and efficacy are considered, the available evidence to date suggests that only beta-blockers can be recommended for the prevention of atrial fibrillation after cardiac surgery. Other treatments might be considered on an individual basis after careful consideration of the patient's potential for side effects.
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Rajagopal et al. (2005) conducted a review in Atrial fibrillation after cardiac surgery. Beta-blockers was evaluated on Prevention of atrial fibrillation. Postoperative atrial fibrillation occurs in 25% to 40% of patients, and available evidence suggests that only beta-blockers can be recommended for its prevention after cardiac surgery.
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