Key result
Exposure to a minimum of 600 MET minutes/week of physical activity was associated with a lower risk of diabetic polyneuropathy in type 1 diabetes patients (OR 0.221; 95% CI 0.068-0.720; p=0.012).
Why the study?
It was unknown whether a personal attitude to physical activity influences the appearance of diabetic polyneuropathy in patients with well-controlled type 1 diabetes mellitus.
Does moderate-to-vigorous physical activity reduce the presence of diabetic polyneuropathy in patients with well-controlled type 1 diabetes mellitus?
Cross-Sectional (n=90)
Does moderate-to-vigorous physical activity reduce the presence of diabetic polyneuropathy in patients with well-controlled type 1 diabetes mellitus?
Odds Ratio: 0.221 (95% CI 0.068–0.72)
p-value: p=0.012
Moderate-to-vigorous physical activity of at least 600 MET minutes/week is associated with a lower prevalence of diabetic polyneuropathy in patients with well-controlled type 1 diabetes.
PA attitude may link to DPN in well-controlled T1DM; cross-sectional data leave causality and practice change open.
Background: The purpose of this study is to access whether a personal attitude to physical activity (PA) may influence the appearance of diabetic polyneuropathy (DPN) patients with well-controlled type 1 diabetes mellitus. Methods: Ninety patients attending the diabetes technology outpatient clinic were enrolled. DPN was investigated according to the Toronto consensus diagnostic criteria. PA was assessed using the International Physical Activity Questionnaire. Results: PA was low in 21.1%, moderate in 42.2% and high in 36.7% of patients. According to Toronto criteria, we defined two categories: the first one with DPN absent or possible (57 (63.3%)) and a second one with DPN certain or probable (33 (36.7%)). The χ2-test of the PA groups and the DPN categories showed a statistically significant difference (p < 0.001), with less neuropathy in patients belonging to the group of moderate/high PA. Exposure to a minimum of 600 MET minutes/week was protective factor against the onset of DPN (odd ratio 0.221, c.i. 0.068–0.720, p = 0.012). Conclusions: This study suggests that DPN is less present in type 1 diabetic patients with good metabolic control and a good personal habit of PA. Moderate-to-vigorous PA of at least 600 MET minutes/week might be a protective factor against DPN.
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Zaccaria et al. (2023) conducted a cross-sectional in Type 1 diabetes mellitus (n=90). Physical activity (minimum of 600 MET minutes/week) vs. Lower physical activity (<600 MET minutes/week) was evaluated on Diabetic polyneuropathy (DPN) (OR 0.221, 95% CI 0.068-0.720, p=0.012). Exposure to a minimum of 600 MET minutes/week of physical activity was associated with a lower risk of diabetic polyneuropathy in type 1 diabetes patients (OR 0.221; 95% CI 0.068-0.720; p=0.012).
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