Key result
A one-time fetal intramuscular injection of 72.3 mcg of digoxin allowed for complete resolution of refractory supraventricular tachycardia and sustained normal sinus rhythm.
Why the study?
Data are limited regarding optimal treatment, route of treatment, and medication dosages for refractory fetal tachycardia.
Does fetal intramuscular injection of digoxin resolve refractory supraventricular tachycardia in a fetus with hydrops fetalis?
Comparison
Fetal intramuscular injection of 72.3 mcg of digoxin
Design
Case presentation
Authors
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May support fetal IM digoxin for refractory SVT; hypothesis-generating and requires prospective trials before adoption.
Case Report (n=1)
Does fetal intramuscular injection of digoxin resolve refractory supraventricular tachycardia in a fetus with hydrops fetalis?
Direct fetal intramuscular injection of digoxin may be an effective therapeutic option for refractory fetal SVT, potentially avoiding maternal toxicity associated with high-dose transplacental medications.
Munoz et al. (2022) conducted a case report in Refractory fetal supraventricular tachycardia complicated by hydrops fetalis (n=1). Fetal intramuscular injection of digoxin was evaluated on Resolution of SVT and sustained normal sinus rhythm. A one-time fetal intramuscular injection of 72.3 mcg of digoxin allowed for complete resolution of refractory supraventricular tachycardia and sustained normal sinus rhythm.
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