Key result
Perceived social support amplified the association of depressive symptoms on pain intensity (interaction score 0.41; 95% CI 0.08-0.74) and did not show a protective function.
Why the study?
Depressive symptoms and chronic pain frequently co-occur in multimorbid patients, and perceived social support may serve as a protective moderator between depression and pain.
Does perceived social support moderate the association between depressive symptoms and pain in elderly multimorbid patients?
Cohort (n=3,189)
Yes
Does perceived social support moderate the association between depressive symptoms and pain in elderly multimorbid patients?
Effect estimate: interaction score 0.41 (95% CI 0.08-0.74)
Perceived social support amplified the association of depressive symptoms on pain intensity rather than showing a protective function in elderly multimorbid patients.
Social support may amplify rather than buffer depressive symptoms' effect on pain intensity in elderly multimorbid patients; hypothesis-generating, requiring prospective confirmation before clinical consideration.
OBJECTIVES: Depressive symptoms and chronic pain are common among patients with multimorbidity creating a complex medical condition for both the patient and the general practitioner. Perceived social support may function as a protective measure. To examine the impact of perceived social support as a potential moderator between depressive symptoms and pain intensity and pain disability in daily activities in multimorbid patients aged 75+. METHOD: Data from 3,189 patients of the German longitudinal cohort study MultiCare were obtained at baseline and follow-ups during 5 years. Multilevel linear mixed-effects analyses were conducted for pain intensity (model 1) and pain disability in daily activities (model 2). The interaction term social support by depression score was included to test for moderation. RESULTS: The interaction between social support and depressive symptoms was significantly associated with the pain intensity score 0.41 (SE=.17; 95-CI[.08;.74]) but not with the pain disability score 0.35 (SE=.19; 95-CI[-.01;.72]). Additionally, men and individuals with medium or higher educational level showed reduced pain intensity and disability scores. Pain disability scores increased with age and depressive symptoms. Increased pain scores were also found for body mass index and burden of multimorbidity. CONCLUSION: Perceived social support amplified the association of depressive symptoms on pain intensity and did not show a protective function. The high scores of perceived social support among the participants may point to the practice of secondary gain due to the patients immense health burden.
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Mallon et al. (2021) conducted a cohort in multimorbidity (n=3,189). Perceived social support and depressive symptoms was evaluated on pain intensity score (interaction score 0.41, 95% CI 0.08-0.74). Perceived social support amplified the association of depressive symptoms on pain intensity (interaction score 0.41; 95% CI 0.08-0.74) and did not show a protective function.
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