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Case series reports isolated vulvar purpura in postmenopausal women, suggesting a mucosal equivalent of dermatoporosis responsive to topical estrogen.
Here, we presented six women with isolated vulvar purpura. No associated lesions such as sclerosis, atrophy, or hypopigmentation were observed. All patients were in postmenopausal period. In this case series, we discussed if a non-blanching purpura could be a component of plasma cell vulvitis or “mucosal porosis”. The possibility of vulvar purpura was questioned as a mucosal equivalent of dermatoporosis which is an age-related degenerative process in the skin. While senile purpura is one of the morphological findings of dermatoporosis, vulvar purpura might be a part of “mucosal porosis”. Rapid response to topical estrogen was remarkable in all patients.
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Kavak et al. (2022) studied this question.
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