A review of the dental management of cleidocranial dysplasia

This is the authors' abstract. We don't add key points for this paper.

Cleidocranial dysplasia, linked to a mutation in the RUNX2 gene, is characterized by defective endochondral and intra-membranous bone formation. General features include a combination of aplasia or hypoplasia of one or both clavicles, a short skull, delayed ossification of the fontanelles and short stature. Dental anomalies include delayed exfoliation of primary teeth, multiple supernumerary teeth and multiple impacted teeth. The dental management of such cases is complicated. This review summarizes the multiple treatment strategies for the dental management of cleidocranial dysplasia. Combined orthodontic and surgical approaches, as well as prosthetic rehabilitation, are discussed. CPD/Clinical Relevance: To highlight the importance of a multidisciplinary, individualized approach to the dental management of patients with cleidocranial dysplasia.