Why the study?
The etiology and underlying mechanism of takotsubo syndrome remain to be fully clarified, questioning whether the term cardiomyopathy is appropriate given evidence of acute myocardial ischemia from microvascular dysfunction.
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Supports adopting "takotsubo syndrome" to reflect microvascular ischemia; leaves open effects on practice and trial design.
Based on the accumulating evidence of acute myocardial ischemia due to microvascular dysfunction as the mechanism underlying this condition, in addition to the fact that the term "cardiomyopathy" literally implies a primary and chronic myocardial disease, it is advisable that the term "takotsubo syndrome" is used until the etiology and underlying mechanism of this condition are fully clarified.
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Doi et al. (2020) studied this question.
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