An enzyme involved in the biosynthesis of cannabichromenic acid was identified in young leaves of Cannabis sativa . The enzyme, named cannabichromenic acid synthase, catalyzed the oxidocyclization of cannabigerolic acid to cannabichromenic acid. The biosynthetic mechanism for the formation of cannabichromenic acid was similar to those of Δ 1 -tetrahydrocannabinolic acid and cannabidiolic acid.
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Morimoto et al. (1997) studied this question.
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