Skeletal Changes Following Renal Transplantation

Of 225 patients who underwent renal transplantation, 100 (44%) later demonstrated osseous changes. Avascular necrosis was seen at the femoral head in 56 and at other sites in 21. Subperiosteal resorption was found in 48, osteosclerosis in 24, and pathological fractures in 30. Other osseous lesions included brown tumors, osteomyelitis, osteopenia, and periostitis. These findings represent most aspects of skeletal involvement in renal failure following renal transplantation.