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Why the study?
Ischemic cardiomyopathy incidence is increasing yearly with rarely any remarkable treatment progress from available drugs, while natural herbal medicine may offer beneficial effects.
Traditional Chinese herbal medicines show potential in animal models for treating ischemic cardiomyopathy through multiple mechanistic pathways.
Does not support clinical use; leaves open translation of animal findings to human ischemic cardiomyopathy trials.
The incidence of ischemic cardiomyopathy (ICM) is increasing yearly, which seriously endangers human health. There is rarely any remarkable progress in the treatment of ICM from the available drugs. Recent research shows that natural herbal medicine may have beneficial effects in the prevention and treatment of cardiovascular diseases. The effective extracts of the herbs may improve myocardial ischemia through various actions, such as hemodynamic, hemorheological, and vascular actions, and on various cell biology aspects, such as intracellular calcium balance, mitochondria function, cell apoptosis, and scavenging free radicals. Here, we review the animal research progress and potential mechanisms in the treatment of ICM using extracts of well-known traditional Chinese herbal medicines.
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Wu et al. (2019) studied this question.
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