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Fabrication of very porous scaffold for regeneration of highly metabolic organs is reported. Polycaprolactone (PCL) powder was mixed with fine salt grains as filler and SLS processed to develop a model including fine flow channel network. The fabricated model was rinsed with water to dissolve the salt, and high porosity of 90% was successfully obtained. Additionally, residual powder in the channels was effectively removed by solution of the filler. Through micro-CT observation, it was confirmed that channels of which diameter was smaller than 1mm were successfully fabricated and repeating branching and merging. Result of culture test is also reported.
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Niino et al. (2006) studied this question.