Evaluation of the relationship between mitral annular calcification and triglyceride-glucose index

Gokhan Gökalp; Nail Burak Özbeyaz; Murat Oğuz Özilhan

doi:10.32322/jhsm.1345325

September 28, 2023Journal of Health Sciences and MedicineOpen Access

Evaluation of the relationship between mitral annular calcification and triglyceride-glucose index

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Why the study?

Mitral annular calcification has a multicomponent etiopathogenesis including insulin resistance, but the relationship between the triglyceride-glucose index and the presence of MAC needed evaluation.

Does a high triglyceride-glucose index predict the presence of mitral annular calcification in adult patients?

Structured PICO

Does a high triglyceride-glucose index predict the presence of mitral annular calcification in adult patients?

P

Population

326 adult patients (159 with mitral annular calcification [MAC] and 167 controls without MAC), mean age 71.4 years, 48.2% male. Exclusions included rheumatic heart valve disease, prosthetic heart valve disease, acute and chronic inflammatory disease, advanced renal failure, liver failure, active malignancy, disease related to calcium metabolism, and steroid therapy.

I

Intervention

High triglyceride-glucose (TyG) index

C

Comparator

Low triglyceride-glucose (TyG) index / Control group without MAC

O

Outcome

Presence of mitral annular calcification (MAC) assessed by transthoracic echocardiographysurrogate

Limitations

Single-center and retrospective study design limits causal inference
Possible selection bias when initially forming the control group
No data or classification regarding the severity of MAC

Implication

A high triglyceride-glucose (TyG) index is an independent predictor of mitral annular calcification, suggesting that insulin resistance plays a significant role in its pathogenesis.

Abstract

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Cite This Study

Gökalp et al. (2023) studied this question.

synapsesocial.com/papers/6a8c7598388b7b6a1fd3cb3a https://doi.org/10.32322/jhsm.1345325

View Full Paper

Ask AI

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Evaluation of the relationship between mitral annular calcification and triglyceride-glucose index

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Evaluation of the relationship between mitral annular calcification and triglyceride-glucose index

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

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