October 12, 2015BMC Pulmonary MedicineOpen Access

Patterns of heart rate variability and cardiac autonomic modulations in controlled and uncontrolled asthmatic patients

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Why the study?

Does asthma control status affect heart rate variability and cardiac autonomic modulations in asthmatic patients?

Population

120 young adults, including 80 asthmatic subjects and 40 healthy subjects, with no history of smoking…

Design

Cross-sectional

Authors

MLMohamed Faisal LutfiQassim University

Discussion

Member takes

Implication

Association of uncontrolled asthma with lower HRV is hypothesis-generating; leaves open causal links to cardiac outcomes or treatment effects.

Structured PICO

Does asthma control status affect heart rate variability and cardiac autonomic modulations in asthmatic patients?

Population

120 young adults, including 80 asthmatic subjects (41 males, 39 females; 37 controlled and 43 uncontrolled) and 40 healthy subjects (22 males, 18 females), with no history of smoking, diabetes mellitus, hypertension, or heart disease.

Comparator

Healthy subjects and uncontrolled asthmatic patients

Outcome

Patterns of heart rate variability (HRV) and cardiac autonomic modulations (LnTP, LnVLF, LnLF, LnHF, LF Norm, HF Norm)surrogate

Asthma control status influences autonomic modulations, with controlled asthma associated with higher HRV and parasympathetic tone compared to uncontrolled asthma, though neither differs from healthy controls when adjusted for heart rate and medications.

Limitations

Respiratory rates were not acknowledged in different study groups while comparing their HRV

Cite This Study

Mohamed Faisal Lutfi (2015) studied this question.

synapsesocial.com/papers/6a8c817d3b2630997c4e06e1 https://doi.org/10.1186/s12890-015-0118-8

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Implication

Association of uncontrolled asthma with lower HRV is hypothesis-generating; leaves open causal links to cardiac outcomes or treatment effects.