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An experimental, immunological analysis was performed to observe whether induced fiber cell formation in the chick lens can be correlated with the biosynthesis of a specific crystallin. As a result of lens inversion, epithelial cells abruptly elongate. In these elongated cells crystallin determinants were uniquely predominant These results seem to indicate that the quiescent genome of lens epithelial cells can be activated with an appropriate artificial stimulus. Moreover, biosynthesis of delta crystallin, at least initially, seems to be strongly correlated with morphological features of lens fiber differentiation.
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Génis-Gálvez et al. (1971) studied this question.
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