Why the study?
Does enoxaparin reduce monocyte adhesion to activated endothelial cells in an in vitro model?
Population
Cultured valvular endothelial cells activated by tumor necrosis factor alpha or lipopolysaccharide, exposed…
Design
Preclinical
Authors
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May protect valvular endothelium from activation in vitro; hypothesis-generating and should not change practice.
Does enoxaparin reduce monocyte adhesion to activated endothelial cells in an in vitro model?
Enoxaparin exhibits a novel anti-inflammatory function by protecting valvular endothelial cells from activation and inhibiting the expression of cell adhesion molecules in vitro.
Mânduțeanu et al. (2002) studied this question.
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