What question did this study set out to answer?

To examine morphological transformations in red blood cells stored in acid citrate dextrose over six weeks and assess the protective effect of adenine using scanning electron microscopy.

February 1, 1972Vox Sanguinis

Scanning Electron Microscope Studies of Red Cell Morphology

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Authors

GLG. H. LongsterScottish National Blood Transfusion Service TBT.F. BuckleyLeeds General Infirmary JSJ. SikorskiLeeds General Infirmary

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Implication

Laboratory study reveals red cell morphological degradation in stored blood, indicating adenine slows reversible structural changes.

Key Points

To examine morphological transformations in red blood cells stored in acid citrate dextrose over six weeks and assess the protective effect of adenine using scanning electron microscopy.
Stored blood samples in acid citrate dextrose over a six-week duration, evaluating the influence of adenine supplementation.
Tracked cellular structural transitions across storage intervals using scanning electron microscopy.
Red blood cells progressively transitioned from normal biconcave discs through intermediate crenated stages to an irreversible spheroidal state.
Adenine supplementation slowed down the structural transformation process during storage.
Membrane alterations were qualitatively determined to be reversible prior to reaching the crenated spheroid stage, beyond which transfused cells undergo rapid destruction.

Cite This Study

Longster et al. (1972) studied this question.

synapsesocial.com/papers/6a8ce41a2fc7b5a11ff55444 https://doi.org/10.1111/j.1423-0410.1972.tb05122.x

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Scanning Electron Microscope Studies of Red Cell Morphology

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Key Points

Cite This Study

Scanning Electron Microscope Studies of Red Cell Morphology

Discussion

Member takes

Implication

Key Points

Cite This Study

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