Effect of Adenine on Stored Erythrocytes Evaluated by Autologous and Homologous Transfusions

Blood obtained from normal volunteers and stored in ACD with or without adenine was evaluated by both tests in vitro and by 24‐hour recovery following transfusion. Significant differences between autologous and homologous transfusions were not detected. The changes that did occur were limited to evidence of lesser erythrocyte breakdown in ACD units fortified with adenine. These units were associated with higher survival values at all storage periods evaluated and displayed over 70 per cent 24‐hour posttransfusion survival even after 42 days of storage.