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April 1, 2020The Indian Journal of Medical ResearchOpen Access

Molecular characterization of hepatitis A virus circulating in Uttar Pradesh, India

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Why the study?

Hepatitis A is a leading cause of acute viral hepatitis in India, but the seropositivity prevalence and predominant circulating strain of HAV in north India needed to be determined.

Population

1615 patients with acute viral hepatitis in north India

Design

Observational cross-sectional study

Authors

SPShantanu PrakashSSSuruchi ShuklaRSRatnam Shukla

Discussion

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Member takes

Overview

May inform regional HAV epidemiology in North Indian children; leaves open need for prospective studies on prevention strategies.

Structured PICO

P
Population
1615 patients with acute viral hepatitis, male:female ratio 1.3:1, mean age 24.31±17.02 yr (range 0-83 yr)
O
Outcome
Seropositivity prevalence of anti-HAV IgM antibodies and predominant circulating strain of HAVsurrogate

Hepatitis A is a common cause of acute viral hepatitis in children in North India, with genotype IIIA being the predominant circulating strain.

Cite This Study

Prakash et al. (2020) studied this question.

synapsesocial.com/papers/6a8ce68e8a9f77207c301b3ehttps://doi.org/10.4103/ijmr.ijmr_429_18
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