Why the study?
The study was conducted to observe the effectiveness of streptokinase in diabetic cases presenting with ST-segment elevation myocardial infarction.
Does streptokinase improve ST segment resolution in diabetic patients presenting with STEMI?
Does streptokinase improve ST segment resolution in diabetic patients presenting with STEMI?
Streptokinase achieved ST-segment resolution in 38.5% of diabetic patients presenting with STEMI.
Answers are grounded in this paper and cite their sources.
May indicate reduced streptokinase efficacy in diabetic STEMI; leaves open need for comparative trials.
Objective: observe effectiveness of streptokinase in diabetic cases presenting with ST-segment elevation myocardial infarction Methodology: In this descriptive case series we enrolled 200 cases fulfilling inclusion/exclusion criteria from the emergency department of Cardiology, Rawalpindi Institute of Cardiology, Rawalpindi. The inj. Streptokinase 1.5 million units diluted in 100 ml of normal saline administered over 1 hour and efficacy was observed. Results: Of 200 diabetic STEMI cases, the effectiveness in terms of ST segment resolution by streptokinase in diabetics presenting with ST-segment elevation myocardial infarction (STEMI) was recorded as 38.5%(n=77). Conclusion: The frequency of effectiveness of streptokinase in diabetic cases for resolution of STEMI is encouraging and it can be used as first line therapy.
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Fayyaz et al. (2021) studied this question.
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