Why the study?
Thrombolytic therapy is a cornerstone of severe PE treatment, but its application in resource-limited settings like Sub-Saharan Africa is not well documented.
Does thrombolytic therapy reduce in-hospital mortality in patients with severe pulmonary embolism in an ICU setting?
Does thrombolytic therapy reduce in-hospital mortality in patients with severe pulmonary embolism in an ICU setting?
Thrombolytic therapy significantly reduces in-hospital mortality in patients with severe pulmonary embolism, highlighting its efficacy even in resource-constrained settings.
Thrombolysis may reduce mortality in severe PE; observational data leaves open need for RCTs before practice change.
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Bifouna et al. (2025) studied this question.
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