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Contextualize the 2022 Extracorporeal Life Support Organization (ELSO) Registry report by reviewing 45 years of technical innovation, clinical trial evidence, and systemic adoption of extracorporeal membrane oxygenation (ECMO).

January 26, 2024ASAIO Journal

ELSO Registry Reports: A New Look

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JZJoseph B. ZwischenbergerUniversity of Kentucky

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Implication

Historical review reports survival milestones exceeding 100,000 patients receiving extracorporeal life support, highlighting 45 years of technical innovation and expanded clinical applications.

Key Points

Contextualize the 2022 Extracorporeal Life Support Organization (ELSO) Registry report by reviewing 45 years of technical innovation, clinical trial evidence, and systemic adoption of extracorporeal membrane oxygenation (ECMO).
Synthesized historical milestones and international registry records documented through the American Society of Artificial Internal Organs (ASAIO) and ELSO since 1975, focusing on modern advances established from 2009 onward.
Tracked technological shifts from custom roller pumps and silicone membranes to modern portable centrifugal circuits, dual-lumen veno-venous cannulas, and advanced surface anticoagulation coatings.
The ELSO international registry reached a milestone of over 100,000 cumulative survivors supported by ECMO, overcoming early trial failure where adult acute respiratory distress syndrome mortality reached 91%.
Transition from veno-arterial cannulation toward veno-venous approaches significantly reduced carotid artery ligation and stroke risks during acute neonatal and adult respiratory failure management.
Indications steadily broadened from neonatal persistent fetal circulation to adult rescue therapies during respiratory pandemics (H1N1 and COVID-19), bridge-to-transplantation, and extracorporeal cardiopulmonary resuscitation (ECPR).

Cite This Study

Joseph B. Zwischenberger (2024) studied this question.

synapsesocial.com/papers/6a8cf6bb1af27387482f06df https://doi.org/10.1097/mat.0000000000002145

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Implication

Historical review reports survival milestones exceeding 100,000 patients receiving extracorporeal life support, highlighting 45 years of technical innovation and expanded clinical applications.

ELSO Registry Reports: A New Look

Discussion

Member takes

Implication

Key Points

Cite This Study

ELSO Registry Reports: A New Look

Discussion

Member takes

Implication

Key Points

Cite This Study

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