What question did this study set out to answer?

To determine the prevalence of coronary artery abnormalities and associated clinical features in patients with incomplete Kawasaki disease compared to complete Kawasaki disease.

June 6, 2007Pediatrics International

Prevalence of coronary artery abnormality in incomplete Kawasaki disease

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Why the study?

What is the prevalence of coronary artery abnormality in patients with incomplete Kawasaki disease compared to complete Kawasaki disease?

Population

15,857 patients with Kawasaki disease (KD) from the 17th Japanese nationwide survey

Design

Cross-sectional

Authors

TSTomoyoshi SonobeJapanese Red Cross Medical Center NKNobuyuki KiyosawaKyoto first Red Cross hospital KTKeiji TsuchiyaJapanese Red Cross Medical Center

Discussion

Member takes

Implication

Incomplete KD may warrant heightened CAA vigilance; cross-sectional data leaves open whether surveillance protocols should differ.

Key Points

To determine the prevalence of coronary artery abnormalities and associated clinical features in patients with incomplete Kawasaki disease compared to complete Kawasaki disease.
Analyzed records from 15,857 patients included in the 17th Japanese nationwide survey of Kawasaki disease.
Defined incomplete Kawasaki disease as presenting with four or fewer principal diagnostic symptoms, regardless of coronary artery status.
Of the 15,857 analyzed cases, 83.9% had complete Kawasaki disease (5–6 symptoms) and 16.1% had incomplete Kawasaki disease (≤4 symptoms).
The prevalence of coronary artery abnormalities was 18.4% in incomplete Kawasaki disease versus 14.2% in complete cases, reaching 18.1% in patients with four symptoms and 19.3% in those with one to three symptoms.
Among all patients diagnosed with coronary artery abnormalities, 14% had four symptoms and 6% had only one to three symptoms.

Structured PICO

What is the prevalence of coronary artery abnormality in patients with incomplete Kawasaki disease compared to complete Kawasaki disease?

Population

15,857 patients with Kawasaki disease (KD) from the 17th Japanese nationwide survey

Comparator

Complete Kawasaki disease (cKD, 5-6 principal symptoms)

Outcome

Prevalence of coronary artery abnormality (CAA)

Incomplete Kawasaki disease is associated with a higher prevalence of coronary artery abnormalities than complete Kawasaki disease, emphasizing that incomplete KD should not be considered a mild form of the disease.

Limitations

Reliability of data for patients with 1-3 symptoms has some limitations

Cite This Study

Sonobe et al. (2007) studied this question.

synapsesocial.com/papers/6a8cfb46fa4b98c6815c2175 https://doi.org/10.1111/j.1442-200x.2007.02396.x

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Prevalence of coronary artery abnormality in incomplete Kawasaki disease

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Prevalence of coronary artery abnormality in incomplete Kawasaki disease

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider