Why the study?
There is a lack of specific indicators and clear diagnostic criteria for incomplete Kawasaki disease, leading to missed timely identification, lack of standardized treatment, and risk of coronary artery lesions.
This review summarizes the diagnosis and management of incomplete Kawasaki disease to aid clinical recognition and prevent coronary artery lesions in children.
Diagnostic criteria for IKD remain elusive; leaves open the need for validated biomarkers in prospective studies.
Kawasaki disease (KD) is a febrile disease mainly observed in children aged <5 years, with medium- and small-vessel vasculitis as the main lesion. Although KD has been reported for more than 50 years and great progress has been made in the etiology and pathology of KD in recent years, there is still a lack of specific indicators for the early diagnosis of KD, especially with more difficulties in the diagnosis of incomplete Kawasaki disease (IKD). At present, there are no clear diagnostic criteria for IKD, which leads to the failure of the timely identification and standardized treatment of IKD in clinical practice and even induce the development of coronary artery lesion. This article reviews the concept, epidemiological features, diagnosis, treatment, and follow-up management of IKD, in order to deepen the understanding of IKD among clinical workers and help to improve the clinical diagnosis and treatment of KD in China.
No takes yet. Share an insight, caveat, or question.
Jiao et al. (2023) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: