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September 11, 2023International Journal of Molecular SciencesOpen Access

Diagnosis, Progress, and Treatment Update of Kawasaki Disease

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Why the study?

Relying solely on original clinical criteria for Kawasaki disease can lead to underdiagnosis or delayed diagnosis, potentially increasing coronary artery complication risk.

Design

Review

Authors

HKHo‐Chang KuoChang Gung University

Discussion

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Implication

Original KD criteria may underdiagnose cases and raise CAL risk; leaves open need for refined diagnostic standards.

Structured PICO

P
Population
Children with Kawasaki disease or suspected Kawasaki disease

This review emphasizes the need for updated diagnostic methods and novel biomarkers to improve the timely diagnosis and management of Kawasaki disease, thereby reducing the risk of coronary artery complications.

Cite This Study

Ho‐Chang Kuo (2023) studied this question.

synapsesocial.com/papers/6a8cfa438c42c2127d301c90https://doi.org/10.3390/ijms241813948
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Bone Marrow–Derived MicroRNA‐223 Works as an Endocrine Genetic Signal in Vascular Endothelial Cells and Participates in Vascular Injury From Kawasaki Disease2017 · 64 citations
  2. 2The role of gut microbiota in immune homeostasis and autoimmunity2012 · 1,462 citations
  3. 3Kawasaki Disease Presenting as Cervical Lymphadenitis or Deep Neck Infection2001 · 50 citations
  4. 4Oxidative stress and Kawasaki disease: how is oxidative stress involved from the acute stage to the chronic stage?2016 · 52 citations
  5. 5miR-27b Suppresses Endothelial Cell Proliferation and Migration by Targeting Smad7 in Kawasaki Disease2018 · 51 citations