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May 1, 2007Expert Review of Cardiovascular Therapy

Treatment with immunoglobulin and aspirin is effective at reducing cardiac complications from 25% to 4.7% in the UK.

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Population

Children aged 6 months to 5 years with Kawasaki disease

Design

Review

Authors

LWLouise WoodRTRobert Tulloh

Discussion

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Overview

Supports immunoglobulin and aspirin to reduce cardiac complications in Kawasaki disease; leaves open need for prospective UK trials before practice change.

Structured PICO

P
Population
Children aged 6 months to 5 years with Kawasaki disease
I
Intervention
Immunoglobulin and aspirin
O
Outcome
Cardiac complications

Kawasaki disease is a major cause of acquired coronary disease in children, and timely treatment with immunoglobulin and aspirin significantly reduces cardiac complications.

Cite This Study

Wood et al. (2007) studied this question.

synapsesocial.com/papers/6a8cfc01ea63fdd6cbf555f3https://doi.org/10.1586/14779072.5.3.553
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Kawasaki disease in children: Figure 12008 · 87 citations
  2. 2Kawasaki Disease2007 · 52 citations
  3. 3Coronary artery changes in patients with Kawasaki disease2004 · 14 citations
  4. 4Kawasaki Disease2009 · 56 citations
  5. 5The diagnosis and management of Kawasaki disease2005 · 53 citations