Why the study?
Does the severity of spinal cord injury affect neurogenic cardiovascular control in conscious rats?
Population
Conscious rats (n=32)
Comparison
Clip compression injury of the spinal cord at T5 vs Sham-operated rats
Design
Preclinical, Randomly allocated into 4 groups
Follow-up
1 week
Authors
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Severity of SCI drives persistent autonomic responses in rats; leaves open translation to human neurogenic cardiovascular control.
Does the severity of spinal cord injury affect neurogenic cardiovascular control in conscious rats?
Dysfunctional cardiovascular control after spinal cord injury is correlated with the severity of injury, with severe injuries causing persistent neurogenic hypotension and autonomic dysreflexia.
Maiorov et al. (1998) studied this question.
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