Effect of Different Concentrations of Silymarin on Performance and Selected Physiological Traits in Local Lambs

S ilymarin is a flavonoid substance that is prepared from Silybum marianum.Silymarin is available as a mixture of flavonolignans, isosilybin, silychristin, silibinin, and silydianin (Saller et al., 2007;Lee et al., 2007).Silymarin mixtures are herbal drugs folk healers have traditionally used to treat several metabolic conditions (Saller et al., 2001).The structure of the flavonolignan phenolics ring of silymarin has pharmacological and antioxidant effects for gastrointestinal and hematologic disorders.Furthermore, silymarin prevents lung, prostate, bladder, and breast cancer (Svobodová et al., 2007).The culture of Silybum marianum is present in Canada, North America, Kashmir, and Mexico; it has reddish-purple flowers and large leaves.The fruits and seeds are the medicinal parts of the plant used for treatment (Dermarderosin, A. 2001).Milk thistle was used for diseases of the spleen, biliary, liver, and stomach (Saller R et al., 2007;Cesanow, et al., 2006).Silymarin has beneficial effects on the general health of sheep and the study found that body weight improved with the administration of Silymarin and increased milk production.Silymarin improves milk quality by increasing the protein level in the milk (Khamisabadi, H. 2020).The Silybum marianum seed extract contains many compounds, such as apigenin, silychristin, and silybin.Furthermore, many oils include oleic acids, palmitic acids, and linoleic acids.Dairy animals graze on this plant a. Silybum marianum did not affect the pH of the rumen.It also resulted in an increase in fatty acids after feeding Silybum marianum.Silymarin has inhibited gluconeogenesis and blood glucose reduction (Mojaddam et al., 2015).