ALTHOUGH the literature is replete with studies of the concentrations and in terrelations of the hormones during the physiological state of pregnancy in A. JV the mare, investigationsinvolving similar studies during the various phases of the estrous cycle of the non′pregnant mare are rare. Zondek (I) reported comparative data upon the estrogenic hormones in the urine of the pregnant and non-pregnant mare, and more recently Cole and Goss (2) cited the presence of gonad tropic hormone in the blood of the latter. However, nowhere in the literature are studies available upon the estrogens of the urine or follicular fluid in relation to the various phenomena of the estrual cycle. For periods beginning in February or April and ending about the middle of July of the years 1937,1938, and 1939 detailed studies were made in the physiology of the non-pregnant mare at the United States Range Live-Stock Experiment Station, Miles City, Montana.
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Mayer et al. (1940) studied this question.