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Nanocomposites of amorphous calcium phosphate (ACP) nanoparticles embedded within chitosan (CHI) have been prepared through an enzymatically assisted route. Cryogenic processing (ISISA) of hydrogel nanocomposites has allowed for the achievement of hierarchical materials (e.g., microchanneled structured ACP/CHI nanocomposites).
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Gutiérrez et al. (2007) studied this question.
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