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June 1, 1997Journal of Neurochemistry

The Globin Fragment LVV‐Hemorphin‐7 Is an Endogenous Ligand for the AT4 Receptor in the Brain

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Population

Sheep brain tissue and bovine adrenal membranes

Comparison

LVV-hemorphin-7 vs Angiotensin IV

Design

Preclinical

Authors

IMIngrid MoellerPerfect Harmony HealthRLRebecca A. LewNational Institute of Standards and TechnologyFMFrederick A.O. MendelsohnNational Institutes of Health

Discussion

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Implication

LVV-hemorphin-7 may serve as endogenous AT4 ligand in CNS; leaves open its in vivo role and human relevance.

Structured PICO

P
Population
Sheep brain tissue and bovine adrenal membranes
I
Intervention
LVV-hemorphin-7
C
Comparator
Angiotensin IV
O
Outcome
Receptor binding affinity and distribution to the angiotensin IV receptorsurrogate

LVV-hemorphin-7 is identified as an endogenous ligand for the angiotensin IV receptor in the central nervous system.

Cite This Study

Moeller et al. (1997) studied this question.

synapsesocial.com/papers/6a8d0ddeb78e02efa68e4e8dhttps://doi.org/10.1046/j.1471-4159.1997.68062530.x
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Also Consider

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  3. 3Astrocytes Synthesize Angiotensinogen in Brain1988 · 338 citations
  4. 4PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT1951 · 318,705 citations