The structural effect of polyanions on the binding type of methylene blue (1) was investigated spectrophotometrically. 1 was bound to poly(potassium styrenesulfonate) (PSS) and poly(sodium 4‐vinylphenylsulfate) (SVS) in the dimeric or slightly aggregated form and to poly(sodium vinylsulfonate) (SVF) and poly(potassium vinyl sulfate) (PVS) in the highly aggregated (polymeric) form. It was found that the flexibility of polyanions plays an important rǒle in the aggregation of bound 1 and that the difference between SO and OSO as binding site is not a significant factor.
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Shirai et al. (1977) studied this question.
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