Why the study?
Not every patient responds optimally to bariatric surgery, and no sufficient method exists pre-operatively to predict who will receive maximum benefit.
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Identifying specific adipose tissue characteristics and patient factors may improve pre-operative prediction of metabolic success following bariatric surgery.
Obesity is an ever-growing public health crisis, and bariatric surgery (BS) has become a valuable tool in ameliorating obesity, along with comorbid conditions such as diabetes, dyslipidemia and hypertension. BS techniques have come a long way, leading to impressive improvements in the health of the majority of patients. Unfortunately, not every patient responds optimally to BS and there is no method that is sufficient to pre-operatively predict who will receive maximum benefit from this surgical intervention. This review focuses on the adipose tissue characteristics and related parameters that may affect outcomes, as well as the potential influences of insulin resistance, BMI, age, psychologic and genetic factors. Understanding the role of these factors may help predict who will benefit the most from BS.
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Keshavjee et al. (2021) studied this question.
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