Population
257 EV71 strains collected in Guangdong province from 2008 to 2010 and 305 GenBank EV71 reference strains…
Design
Other
Authors
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Supports intensified HFMD surveillance amid EV71 C4 expansion; leaves open functional consequences of VP1 substitutions.
The increased reporting of HFMD in China since 2007 reflects a real increase in viral spread of EV71 subgenogroup C4, accompanied by regular amino acid substitutions in the VP1 gene.
Guan et al. (2012) studied this question.
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